Carboxyphosphamide
WebCarboxyphosphamide DBMET01088 Nornitrogen mustard DBMET01125 Reaction type Not Available Direction Major circulating metabolite? No Spontaneous? No Activity active References Kanehisa M, Goto S, Kawashima S, Okuno Y, Hattori M: The KEGG resource for deciphering the genome. Nucleic Acids Res. 2004 Jan 1;32 (Database issue):D277 … WebPage 1/8 Safety Data Sheet acc. to OSHA HCS Printing date 08/17/2024 Revision date 08/17/2024 53.1.21 1 Identification · Product identifier · Trade name: Carboxyphosphamide · Article number: 34052 · CAS Number: 22788-18-7 · Application of the substance / the mixture This product is for research use - Not for human or veterinary …
Carboxyphosphamide
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WebNov 18, 1992 · Carboxyphosphamide is an inactive metabolite of cyclophosphamide, which is a widely used antineoplastic drug. Deficiencies in the production of this … WebAlcohol dehydrogenase and aldo-keto reductase also play a minor role in the elimination of aldophosphamide by reducing them to alcophosphamide. In contrast, the oxidation of aldophosphamide to carboxyphosphamide, catalyzed by ALDH1A1 and ALDH3A1, is an important inactivation pathway. Less than 20% of the CP dose is eliminated in the urine …
Webcarboxyphosphamide, a compound with weaker antineoplastic capabilities, which is the primary recoverable urinary constituent of the drug. '',19 Interestingly, the phosphamidase activity necessary for the initial conversion in the liver has been demonstrated in the urothelium of the rat bladder. 26 WebCarboxyphosphamide KEGG COMPOUND Manual Xrefs Databases C07646: KEGG COMPOUND HMDB0060449: HMDB HMDB0060687: HMDB View more database links: …
WebCyclophosphamide is approved to be used alone or with other drugs to treat: Acute lymphoblastic leukemia (ALL) in children. Acute monocytic leukemia. Acute myeloid …
Web英文名称:Carboxyphosphamide . Cayman Chemical: 34052-5: ¥询价/5mg: 加入购物车: 中文名称:羧基磷酰胺 . 英文名称:Carboxyphosphamide . Cayman Chemical: 34052-25: ¥询价/25mg: 加入购物车: 中文名称:羧基磷酰胺 . 英文名称:Carboxyphosphamide . Cayman Chemical: 34052-10: ¥询价/10mg: 加入 ...
WebJul 4, 2024 · National Center for Biotechnology Information crystal palace 1st teamWeband carboxyphosphamide (CARB) was carried out as described in [8]. For HPLC determination and incubation experiments with rat serum ultrafiltrate and rat serum, see [9]. dyad wooden cat litter box largeWeb欢迎您访问武汉艾美捷科技有限公司官方网站! dy-a-flex clutchWebSep 30, 2012 · Cyclophosphamide, in which the nitrogen-mustard group (bis-chloroethylamine) is attached to an oxazaphosphorine ring, was introduced as an … dyafull com srlWebNov 1, 2024 · Cyclophosphamide is activated to form 4-hydroxycyclophosphamide, which is in equilibrium with its ring-open tautomer aldophosphamide. 4hydroxycyclophosphamide and aldophosphamide can undergo oxidation by aldehyde dehydrogenases to form the inactive metabolites 4-ketocyclophosphamide and carboxyphosphamide, respectively. crystal palace 2019/20 seasonCarboxyphosphamide C7H15Cl2N2O4P CID 31515 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. dyafa 1 - hotel apartmentsWebPlasma concentrations of cyclophosphamide and the metabolites 4-ketocyclophosphamide, dechloroethylcyclophosphamide and carboxyphosphamide were determined on days 1, 2 and 3 of each course. A population pharmacokinetic model for cyclophosphamide was developed using non-linear mixed effects modelling and metabolite AUC values were … dy-a-flex