Cthrc1 cancer

Author: lbxh

August undefined, 2024

WebJul 19, 2024 · Collagen triple helix repeat containing-1 (CTHRC1), highly expressed in multiple human solid tumors, has been identified as a tumor associated protein. However, its specific role and mechanism with immune infiltrates in gastric cancer are still unclear. In this study, we systematically explored and validated the expression and prognostic value of … WebJun 20, 2024 · CTHRC1 is a secretory glycoprotein that was discovered while differentially expressed genes were screened after severe arterial injury in rats. 6,7 Subsequently, researchers reported that CTHRC1 is …

CTHRC1 May Serve As A Prognostic Biomarker For Hepatocellular …

WebCollagen triple helix repeat containing 1 (CTHRC1) is a secreted glycoprotein that decreases the deposition of collagen matrix and accelerates tumor metastasis. However, the relationship between CTHRC1 and the outcomes of head and neck squamous cell carcinoma (HNSCC) and tumor‑infiltrating lymphocytes remains unclear. In the present … WebMar 30, 2012 · The gene, collagen triple helix repeat containing 1 (CTHRC1), has been reported to increase in several kinds of human solid cancers and is associated with tumor invasion and metastasis.To date, the expression and function of CTHRC1 in gastric cancer (GC) have not been reported. increase the thickness of life

Cthrc1 Is a Novel Inhibitor of Transforming Growth Factor-β …

WebThis study aimed to investigate the prognostic value of CTHRC1, and further explore its association with immune infiltration in breast cancer. Javascript is currently disabled in … WebOct 22, 2024 · The association of CTHRC1 with tumor progression is demonstrated in various human cancers, including hepatocellular carcinoma, gastric cancer, pancreatic cancer, GIST and colorectal cancer (1-3).In a meta-analysis done by Wang et al., the results revealed correlation of CTHRC1 expression with TNM stage in gastric cancer, … WebNov 14, 2024 · Although recent researches have reported that CTHRC1 upregulation in breast cancer promoting cell proliferation, invasion and migration could be through activating GSK-3β/β-catenin signaling, Citation 41 the exact mechanisms of CTHRC1 involvement in breast cancer remains unclear. Therefore, high expression of CTHRC1 … increase the time

CTHRC1 Gene - GeneCards CTHR1 Protein CTHR1 …

CTHRC1 targeted by miR-30a-5p regulates cell adhesion, invasion …

WebFeb 22, 2007 · We originally identified collagen triple helix repeat containing-1 (Cthrc1) in a screen for differentially expressed genes in normal versus balloon-injured arteries. 1 In … WebMar 21, 2024 · Bioinformatics method. LUAD related data sets were acquired from Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA), as shown in Table 1.Expression differences of CTHRC1 between normal tissue and LUAD tissue were tested by t-test, and the effect of CTHRC1 expression on patient’s prognosis was detected with … increase the typing speedWebSep 28, 2024 · CTHRC1, collagen triple helix repeat containing-1; CAF, cancer-associated fibroblast; CM, conditioned media. CAFs promote EMT alterations in BC cells by secreting CTHRC1 EMT is a recognized biological process that plays a key role in tumor metastasis, and is characterized by the loss of epithelial markers (such as E-cadherin) … increase the video quality

"WebCTHRC1. PROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. CTHRC1 INFORMATION. Proteini. Full gene name according to HGNC. Collagen triple helix repeat containing 1. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. CTHRC1. " - Cthrc1 cancer

Cthrc1 cancer

Human Collagen triple helix repeat-containing protein 1(CTHRC1…

WebMay 13, 2024 · Here, by comparing the gene expression patterns in primary colorectal cancer (CRC) patients with or without metastasis, we found … WebMar 1, 2024 · Collagen triple helix repeat containing 1 (CTHRC1) is a glycosylated protein secreted during tissue repair, which reduces collagen matrix deposition and …

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WebJul 19, 2024 · Collagen triple helix repeat containing-1 (CTHRC1), highly expressed in multiple human solid tumors, has been identified as a tumor associated protein. …

WebCollagen triple helix repeat containing 1 is a protein that in humans is encoded by the CTHRC1 gene. Function. This locus encodes a protein that may play a role in the cellular response to arterial injury through involvement in vascular remodeling. Mutations at this locus have been associated with Barrett's esophagus and esophageal adenocarcinoma. WebOct 6, 2024 · In the current study, we comprehensively analyzed CTHRC1 in distinct human cancer subtypes for the first time and find more closely CTHRC1-associated cancer …

WebMar 21, 2024 · CTHRC1 (Collagen Triple Helix Repeat Containing 1) is a Protein Coding gene. Diseases associated with CTHRC1 include Barrett Esophagus and Adenocarcinoma . Among its related pathways are Wnt … WebOct 26, 2024 · The function of collagen triple helix repeat containing 1 (CTHRC1) as an oncogene has been reported in a growing number of publications. Bioinformatics methods represent a beneficial approach to examine the mechanism and function of the CTHRC1 gene in the disease process of cancers from a pan-cancer perspective. In this study, …

WebCTHRC1 has a role in pancreatic cancer progression and metastasis by regulating migration and adhesion activities of cancer cells. PMID: 23222813; Data indicate that the upregulated expression of collagen triple helix repeat containing 1 (CTHRC1) in gastric carcinogenesis contributes to tumor cell invasion and metastasis.

WebFeb 22, 2007 · We originally identified collagen triple helix repeat containing-1 (Cthrc1) in a screen for differentially expressed genes in normal versus balloon-injured arteries. 1 In the vasculature, Cthrc1 expression is limited to injured tissue, where it is induced abundantly in adventitial fibroblasts and neointimal smooth muscle cells (SMCs). … increase the value of the businessWebMar 21, 2024 · Single-Cell RNA Sequencing Analysis Reveals a Crucial Role for CTHRC1 (Collagen Triple Helix Repeat Containing 1) Cardiac Fibroblasts After Myocardial … increase the value of your homeWebApr 28, 2024 · CTHRC1 and LOXL2 are prominently upregulated pan-cancer matrisome genes. High CTHRC1 and LOXL2 expression is associated with disease progression and … increase the united states’ “hard power.”WebJun 20, 2024 · This study aimed to investigate the prognostic value of CTHRC1, and further explore its association with immune infiltration in breast cancer. Methods: CTHRC1 … increase the word countWebApr 10, 2024 · The strong invasive and metastatic nature of non-small cell lung cancer (NSCLC) leads to poor prognosis. Collagen triple helix repeat containing 1 (CTHRC1) is involved in cell migration, motility and invasion. The object of this study is to investigate the involvement of CTHRC1 in NSCLC invasion and metastasis. A proteomic analysis was … increase the uncertaintyWebJ Cancer 2016; 7(15):2213-2220. doi:10.7150/jca.16539 This issue Cite. Review. Multidimensional Roles of Collagen Triple Helix Repeat Containing 1 (CTHRC1) in Malignant Cancers . Neng Jiang 1*, … increase the turnoverWebIdentification and Verification of Potential Biomarkers in Gastric Cancer By Integrated Bioinformatic Analysis. Chenyu Sun, Yue ... Collagen Type X Alpha 1 Chain (COL10A1), … increase the value limited