Irf1 molecular weight

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August undefined, 2024

WebIRF1 Protein Molecular Weight & PI . The parameters have been computed for the following feature . FT CHAIN 1-325 Interferon regulatory factor 1. Molecular weight (Da) 36502.21 Theoretical pI . 5.22 Bulk Order of Recombinant IRF1 Protein . Please Leave Us a Message if you have any questions regarding bulk price quote of our products on the ... WebMar 29, 2024 · IRF1 and IRF2 also appear to be important in regulating DC subset development— Irf −/− mice show a loss of splenic and epidermal DCs (due to augmented type I IFN signaling) ( 109, 110) whereas Irf1−/− exhibit an increase in pDCs and a decrease in CD8 + DCs in mice, along with an increase of IL-10 and TGF-β ( 111 ).

Interferon regulatory factor 1 (IRF-1) promotes intestinal group 3 ...

• Harada H, Taniguchi T, Tanaka N (1999). "The role of interferon regulatory factors in the interferon system and cell growth control". Biochimie. 80 (8–9): 641–50. doi:10.1016/S0300-9084(99)80017-0. PMID 9865486. • Pitha PM, Au WC, Lowther W, Juang YT, Schafer SL, Burysek L, Hiscott J, Moore PA (1999). "Role of the interferon regulatory factors (IRFs) in virus-mediated signaling and regulation of cell growth". Biochimie. 80 (8–9): 651–8. doi:10.1016/S030… • Harada H, Taniguchi T, Tanaka N (1999). "The role of interferon regulatory factors in the interferon system and cell growth control". Biochimie. 80 (8–9): 641–50. doi:10.1016/S0300-9084(99)80017-0. PMID 9865486. • Pitha PM, Au WC, Lowther W, Juang YT, Schafer SL, Burysek L, Hiscott J, Moore PA (1999). "Role of the interferon regulatory factors (IRFs) in virus-mediated signaling and regulation of cell growth". Biochimie. 80 (8–9): 651–8. doi:10.1016/S0300-9084(99… WebApr 15, 2024 · Recently, the therapeutic combination of atezolizumab and bevacizumab was widely used to treat advanced hepatocellular carcinoma (HCC). According to recent clinical trials, immune checkpoint inhibitors (ICIs) and molecular target agents are expected to be key therapeutic strategies in the future. Nonetheless, the mechanisms underlying … curly max pro

Buy Recombinant Human IRF1, N-His - antibodysystem.com

WebWhen using primary antibodies produced in mouse to detect proteins with a molecular weight in the range of 50 kDa, we recommend using Rabbit Anti-Mouse IgG (Light Chain … WebSep 16, 2024 · Retained uremic toxins can be divided into three groups according to physicochemical characteristics: small water-soluble compounds (molecular weight (MW) < 500 Da), middle-molecules (500 Da <... WebInterferon regulatory factor 1 (IRF1) is a tumor suppressor gene often found downregulated in breast cancers; this low expression correlates with endocrine therapy resistance (Bouker et al., 2004, 2005, 2007; Gu et al., 2002 ). Approximately, 30% of cancerous breast lesions have allelic loss of IRF1 when compared with the adjacent normal breast ... curly maxis match hair

IRF1-mediated downregulation of PGC1α contributes to ... - Nature

IRF1 is critical for the TNF-driven interferon response in

WebDescription Product name Recombinant Human IRF1 protein (His tag) Purity > 90 % SDS-PAGE. NULL Endotoxin level < 1.000 Eu/µg Expression system Escherichia coli Accession … WebApr 4, 2024 · IRF-1 is an important signaling protein in the interferon pathway. It not only activates gene expression as a transcription factor, but may perpetuate disease by leading to a dysregulated epigenome. Data suggest that interferon regulatory factors 1 and 2 (IRF1 and IRF2) may serve as potential targets of therapy. curly mckibbyWebIRF1 as a transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. The calculated molecular weight of IRF1 is 37 kDa, but … curly maxis match cc

"WebWestern blot analysis of HeLa cells, untreated or treated with Human Interferon-γ (hIFN-γ) #8901 (100 ng/ml, 4 hr), using IRF-1 (D5E4) XP ® Rabbit mAb. Western blot analysis of … " - Irf1 molecular weight

Irf1 molecular weight

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WebMar 21, 2024 · IRF1 (Interferon Regulatory Factor 1) is a Protein Coding gene. Diseases associated with IRF1 include Lung Cancer and Gastric Cancer. Among its related pathways are Bacterial infections in CF airways and Overview of interferons-mediated signaling … HBB (Hemoglobin Subunit Beta) is a Protein Coding gene. Diseases associated with … Gene Ontology (GO) - Molecular Function for MET Gene. GO ID Qualified GO term … VCAM1 (Vascular Cell Adhesion Molecule 1) is a Protein Coding gene. Diseases … Complete information for IWS1 gene (Protein Coding), Interacts With SUPT6H, … PHGDH (Phosphoglycerate Dehydrogenase) is a Protein Coding gene. Diseases … CCL2 (C-C Motif Chemokine Ligand 2) is a Protein Coding gene. Diseases … IFITM1 (Interferon Induced Transmembrane Protein 1) is a Protein Coding gene. … CCL19 (C-C Motif Chemokine Ligand 19) is a Protein Coding gene. Diseases … IGFBP7 (Insulin Like Growth Factor Binding Protein 7) is a Protein Coding gene. … CDKN1B (Cyclin Dependent Kinase Inhibitor 1B) is a Protein Coding gene. Diseases … WebDec 27, 2024 · Results: IRF1 was identified as a novel TF that suppresses KPNA2 gene expression. We observed that IRF1 expression was lower in cancerous tissues than in normal lung tissues and that its low expression was correlated with poor prognosis in …

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WebJan 15, 2024 · Interferon regulatory factor 1 (IRF1) is an important regulator in controlling the transcription of type I interferon genes, and its functions have been well-characterized in mammals, birds and fish. However, little information is available regarding the function of amphibian IRF1. WebDec 1, 2024 · LcIRF2, LcIRF5, LcIRF6, LcIRF10, and LcIRF11 have ORF of 954, 1476, 1473, 1206, and 792 bp, encoding 318, 492, 491, 402, and 264 aa, with a predicted molecular …

WebJul 8, 2024 · IRF1 expression is associated with the expression of IFNβ, which leads to the activation of the JAK-STAT pathway. ... Consistently, molecular function enrichment … WebApr 10, 2024 · The predicted theoretical isoelectric point of pIgR amino acid sequence is 5.92, and theoretical molecular weight is 37.48 kDa, and the first 19 amino acids are signal peptides. It is predicted that there may be an N-linked glycosylation site (N 34 LTV) in the extracellular domain (Fig. 1). Download : Download high-res image (4MB)

WebJan 15, 2024 · Molecular and functional characterization of interferon regulatory factor 1 (IRF1) ... 10 μg/g body weight] for 3 h, whose spleen and kidney were used for the extraction of total RNA by using Trizol Reagent (Invitrogen). The first-strand cDNA was synthesized from above total RNA and served as template to amplify ORF sequence of Xt-IRF1 by PCR ... WebJun 30, 2016 · Besides CCL2, the transcription factor IRF1, which has proapoptotic activities was significantly upregulated after IL6/sgp80 or OSM stimulation. qRT-PCR revealed a rapid (within 2 hours) and strong (10- to 12-fold) induction of IRF1 mRNA after OSM or IL6/sgp80 stimulation in HeLa and SW756 cells (Fig. 6A; P <0.0001).

WebApr 4, 2024 · IRF1 is involved in TLR- and cytokine-mediated signaling in human myometrium. 5AZ had a protective effect after MI by potentiation of IRF1 sumoylation and …

WebDisruption of this signaling pathway by deletion of Irf1 or Stat1 protects mouse macrophages from TNF-α- and IFN-γ- induced cell death, as well as induced holopsia deletion in the absence of Irf1. Similarly, Stat1-/- mice were protected from TNF- and IFN-γ- induced death. Figure 4. TNF-α and IFN-γ induce JAK/STAT1/IRF1 signaling and PANoptosis curly meWebMay 5, 2014 · Interleukin 1 (IL-1) is a pleiotropic cytokine that regulates immune and inflammatory responses by inducing the expression of a variety of pro-inflammatory cytokines and chemokines. curlymeWebObjectives: Although it has been reported that Interferon regulatory factor 1 (IRF1) inhibits Mycobacterium tuberculosis (Mtb) infection via inducible nitric oxide synthase (iNOS) in mice, how it counteracts with mycobacterial infection in human remains largely obscure. curlyme collectionWebMay 5, 2014 · Cellular & Molecular Immunology - K63-linked polyubiquitination of IRF1: an essential step in the IL-1 signaling cascade ... Adding weight to this was the observation that SKI-1, ... curlyme.comWebIRF1-regulated gene expression equipped low-grade PDAC cells with distinctive properties related to antigen presentation and processing as well as responsiveness to IFN stimulation. curlyme discount codesWebSep 29, 2024 · Given that IRF-1 is well known to molecularly act downstream of IFN-γ signaling, we also subjected mice lacking IFN-γ to C. rodentium infection. However, compared to control mice, we observed no... curly meat market templeWebIRF1 Antibodies. Antibodies that detect IRF1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry and Flow Cytometry. These antibodies target IRF1 in Human, Mouse and Rat samples. Our IRF1 polyclonal, recombinant monoclonal and monoclonal antibodies are developed ... curlyme.com reviews