Web23 mrt. 2024 · For nearly five decades, cisplatin has played an important role as a standard chemotherapeutic agent and been prescribed to 10-20% of all cancer patients. Although nephrotoxicity associated with platinum-based agents is well recognized, treatment of cisplatin-induced acute kidney injury is mainly su … WebCarboplatin is also a platinum-based agent with a lower po-tential for nephrotoxicity compared with cisplatin but can be nephrotoxicatmyeloablativedosesof.800mg/m2 …
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Web10 mrt. 2015 · Alkylating agents are a class of antineoplastic or anticancer drugs which act by inhibiting the transcription of DNA into RNA and thereby stopping the protein synthesis. Alkylating agents substitute alkyl groups for hydrogen atoms on DNA, resulting in the formation of cross links within the DNA chai … Alkylating Agents Review Web21 mei 2024 · Kidney. Fluconazole (tissue: plasma ratio of 0.77–0.89), voriconazole (tissue concentrations 6.47 μg/g), the polyenes (10 times serum), and flucytosine (3 times … can bees see red flowers
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WebThose at highest risk include adults older than 75 years; persons with diabetes or preexisting chronic kidney disease; persons with medical problems such as cardiac failure, liver … WebDrug dosing requirements for hypoglycemic agents in patients with chronic kidney disease are listed in Table 5. 4, 18, 19 Because metformin (Glucophage) is 90 to 100 percent renally excreted, 18 ... Web12 jun. 2024 · National Center for Biotechnology Information can bees see colour