WebExpression levels of Mitochondria-Associated Membranes proteins phosphatidylserine decarboxylase, DRP1, ATAD3A or TSPO were greatly reduced by mitotane as assessed by western blot analyses. Mitotane exposure markedly altered endogenous Mitochondria-Associated Membranes integrity and reduced the magnitude of mitochondria and the … WebApr 24, 2015 · Thus, mitochondrial phosphatidylserine decarboxylase (PSD) appears to play an essential role in the autonomous generation of PE within the organelle. ... When MBP-His 6-Δ34PkPSD was induced for 20 min, more than 80% of the protein was found in the proenzyme form (Fig. 2A), and cell extracts from these preparations were used to follow …
From Protease to Decarboxylase - Journal of Biological Chemistry
WebApr 24, 2015 · Phosphatidylserine decarboxylase (PSDs) play a central role in the synthesis of phosphatidylethanolamine in numerous species of prokaryotes and eukaryotes. PSDs are unusual decarboxylase containing a pyruvoyl prosthetic group within the active site. The covalently attached pyruvoyl moiety is formed … WebFeb 1, 2009 · Phosphatidylserine decarboxylase proenzyme 2 (CRP-44) plays a central role in phospholipid metabolism and in the inter-organelle trafficking of phosphatidylserine by catalyzing the formation of ... small tillers reviews
Human Metabolome Database: HMDB0284357 …
WebThe phosphatidylserine decarboxylase pathway has a significant role in maintaining phospholipid homeostasis in adult skeletal muscle. Moreover, phosphatidylserine decarboxylase is essential for maintenance of mitochondrial … WebMar 5, 1990 · Phosphatidylserine decarboxylase from Escherichia coli uses a pyruvate group as the enzyme cofactor (Satre, M., and Kennedy, E. P. (1978) J. Biol. Chem. 253, 479-483). Comparison of the DNA sequence of the psd gene with the partial amino acid sequence of the mature gene product suggests that the two … WebSep 4, 1997 · Phosphatidylserine decarboxylase (PSD) is an important enzyme in the synthesis of phosphatidylethanolamine in both prokaryotes and eukaryotes. The cloned … highway to hell 18 räder aus stahl