Phosphopantetheine attachment site
WebPhosphopantetheine tethering is a posttranslational modification that takes place on the active site serine of carrier proteins 138 – ‘acyl carrier proteins ... which forms the 4′PPan cofactor attachment site. This α-helical region as well as two other α-helical segments (helix 1, residues 3–15 and helix 4, ... WebJan 10, 2024 · To obtain active CAR enzyme, a phosphopantetheine group must be attached covalently to a conserved serine in the PCP domain mediated by a suitable …
Phosphopantetheine attachment site
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WebMar 21, 2024 · This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ( [ACP]) domain. ( FAS_HUMAN,P49327 ) (Microbial infection) Fatty acid synthetase activity is required for SARS coronavirus-2/SARS-CoV-2 replication. ( FAS_HUMAN,P49327 ) http://pfam-legacy.xfam.org/family/PF00550
Web4'-Phosphopantetheine C11H23N2O7PS CID 115254 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological ... WebThe bond was not formed in a point mutant lacking the phosphopantetheine attachment site. Competition experiments with various amino acids indicated that the reaction was …
WebApr 26, 2024 · In addition, it showed a close relationship with the phosphopantetheine attachment site protein (IPR006162) and acyl carrier protein of super family SSF47336 (IPR009081). It also shares similarities with the peptide chains of IPR020806 polyketide synthase, phosphopantetheine-binding domain, and others including IPR020845, … WebSep 29, 2024 · Phosphopantetheine attachment site. A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the …
WebJan 6, 2024 · The Psc_Aza_B gene is predicted to encode a non-reducing polyketide synthase composed of ve modules: ACP transacylase, β-ketoacyl synthase, acyltransferase phosphopantetheine attachment site and ...
WebPhosphopantetheine attachment site Provide feedback. A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. This family includes members not included in Prosite. dutch performante net worthWebThe human NDUFAB1 protein contains a phosphopantetheine attachment site (DLGLDSLDQVEIIMAM), unique for acyl carrier proteins, and an EF-hand calcium binding domain (DIDAEKLMCPQEI). Transcripts of this gene are found in … dutch payroll softwareWebACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process Alternate IDs None Definition Binding an acyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the acyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme ... dutch performance shopWebACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process: Interacting selectively and non-covalently with the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP) as part of the process of fatty acid biosynthesis. GO:0009987: cellular process dutch performance productsWeb[0005] This invention relates to a method of treatment, in particular to a method for lowering blood pressue levels in mammals and to compounds and compositions for use in such me dutch pay calculatorWebACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process Definition: Interacting selectively and non-covalently with the attachment site of the … dutch performance facilities b.vWebAcp phosphopantetheine attachment site binding involved in fatty acid biosynthetic process Pfam Domain Function. PP-binding ; Transmembrane Regions Not Available Cellular … crysis 2 pc cover